Brello Health's semaglutide pricing looks attractive: $399 for 3 months works out to just $133/month. But that 3-month upfront commitment is non-negotiable, and after using their service for one full cycle, I have mixed feelings about whether the savings are worth the trade-offs.

Brello Health Overview

Brello Health is a newer telehealth platform (launched 2023) that operates as the direct-to-consumer arm of Southend Pharmacy in Houston. They focus exclusively on GLP-1 weight loss medications, offering both semaglutide and tirzepatide with included coaching.

Their model is built around 10-week (roughly 3-month) subscription cycles with no option for monthly billing. You commit upfront or you don't use the service.

Pricing Breakdown

Here's what $399 gets you for 3 months of semaglutide:

Cost: $399 every 10 weeks ($133/month equivalent)
Included: Compounded semaglutide, syringes, supplies, provider oversight, coaching, shipping
Payment: Billed every 10 weeks, upfront payment required

Compared to the market:

Cheaper: CoreAge Rx ($99/month)
Similar: Orderly Meds ($149/month), other mid-tier services
More expensive: Premium services ($200-400/month)

So at $133/month, Brello sits in the affordable-to-mid-range. Not the cheapest, but competitive.

My 3-Month Experience

Sign-Up Process

I completed Brello's online intake form, which took about 20 minutes. It was thorough—medical history, weight goals, current medications, etc.

Within 24 hours, a provider reviewed my information and approved me for semaglutide. There was no live video consultation—everything was done asynchronously through forms and messages.

I was immediately charged $399 for the first 3 months. No trial period, no month-to-month option.

First Delivery

My medication arrived 6 days after approval. Not terrible, but not fast either. The package contained:

Three vials of compounded semaglutide with B6. Syringes and needles for 3 months. Alcohol wipes. Basic instruction sheet.

The packaging was functional but not particularly impressive. Everything was properly temperature-controlled and sealed, but it felt more utilitarian than professional compared to larger competitors.

The B6 Addition

Brello adds vitamin B6 (pyridoxine) to their semaglutide formulation. They claim this helps reduce nausea and other side effects.

Honestly? I couldn't tell if it made a difference. I still experienced the typical semaglutide side effects—mild nausea with dose increases, occasional digestive changes. Maybe it would have been worse without B6, but there's no way to know.

Results: Did The Medication Work?

Yes, the semaglutide itself works fine. I started at 0.25mg weekly and titrated up to 1.0mg over 3 months, following standard dosing protocols.

Effects I experienced:

Significant appetite suppression. Reduced food noise and cravings. Feeling satisfied with smaller portions. Better control over eating impulses.

My results over 3 months:

Weight lost: 19 pounds
Side effects: Mild nausea for 2-3 days after dose increases, occasional constipation
Energy: Slightly lower than usual, but manageable
Cravings: Dramatically reduced

The medication quality is fine. It works like any other compounded semaglutide I've tried.

The "Personalized Coaching"

Brello includes coaching as part of their service. Here's what that actually looks like:

Weekly check-in messages through the portal. Educational articles about weight loss and nutrition. Automated progress tracking. Occasional responses from human coaches.

The coaching feels more automated than truly personalized. You get generic tips and encouragement, not customized guidance based on your specific situation.

It's better than nothing, but calling it "personalized" is a stretch.

Customer Service Issues

This is where Brello really lost points for me. I contacted customer service four times during my 3 months:

Question about dosing: Took 48 hours to get a response
Shipping delay: Waited 3 days for reply, then got a generic answer
Side effects concern: Response came next day but felt rushed and unhelpful
Billing question: Took 2+ days and multiple follow-ups

Brello's customer service isn't terrible, but it's consistently slow. When you have questions about medication or your health, waiting days for answers is frustrating.

The Commitment Problem

The $399 upfront, 3-month commitment is Brello's biggest issue for me.

Why it's problematic:

$399 is a significant upfront cost. You can't try it for one month to see if it works for you. If you have side effects or want to switch, you're stuck. No flexibility to pause or adjust your treatment. Makes it harder to cancel if you're unhappy.

The counterargument:

Lowers the monthly cost to $133. Ensures you stick with treatment long enough to see results. Simplifies billing (one charge every 10 weeks).

For me, the lack of flexibility outweighs the cost savings. I'd rather pay a bit more per month and have the option to cancel anytime.

Trustpilot Reviews Match My Experience

Brello has a 3.7/5 rating on Trustpilot with over 1,500 reviews. Looking through them, common themes match what I experienced:

Positive: Affordable pricing, medication works, straightforward process. Negative: Slow customer service, hard to cancel, commitment requirement, shipping delays.

This isn't just my experience—it's consistent across hundreds of reviews.

Who Should Choose Brello Health?

Brello Health might work for:

People who can afford $399 upfront. Those committed to trying semaglutide for at least 3 months. Anyone comfortable with slower customer service. Budget-conscious users who prioritize price over support.

Probably not right for:

People who want month-to-month flexibility. Those who value responsive customer service. Anyone wanting to test the service for one month first. Users who prefer live consultations. People who need white-glove support.

My Verdict

Brello Health offers functional medication at a competitive price, but the 3-month commitment and subpar customer service make it hard to recommend enthusiastically.

The medication works—that's not the issue. It's everything around the medication that feels lacking: slow support, inflexible commitment, generic coaching, delayed shipping.

Rating: 4.2/5 stars

It's an okay service that gets the job done, but there are better options if you value flexibility and support.

Bottom Line

If you're absolutely certain you want to commit to semaglutide for 3+ months and you're comfortable with slower customer service, Brello can save you some money.

But for most people, I'd recommend paying slightly more for a service with better support, flexibility, and responsiveness. The peace of mind is worth the extra cost.