Brello Health offers tirzepatide at $499 for 3 months, which works out to $166/month—a competitive price. But there's a catch: you have to commit to 3 months upfront. After using their service for one full cycle, here's my honest take on whether that commitment is worth it.

What is Brello Health?

Brello Health is a relatively new telehealth company (founded 2023) that operates as the direct-to-consumer arm of Southend Pharmacy in Houston, Texas. They specialize in GLP-1 medications for weight management, offering both semaglutide and tirzepatide with personalized coaching.

They've grown quickly—over 70,000 members according to their site—and position themselves as an affordable, accessible option for GLP-1 weight loss.

The Pricing: $499 for 3 Months

Here's how Brello's pricing works for tirzepatide:

Upfront cost: $499 for 10-week supply (approximately 3 months)
Monthly equivalent: $166/month
What's included: Medication, supplies, coaching, provider oversight, shipping

You're billed every 10 weeks at this rate. There's no option to just try one month—you commit to the 3-month cycle from the start.

Compared to competitors:

Cheaper than: Premium services ($300-500/month). More expensive than: CoreAge Rx ($99/month), Orderly Meds ($299/month).

So it's competitively priced, but not the cheapest option available.

My Experience: 3 Months with Brello Health

Getting Started

The signup process was straightforward. I completed an online intake form, which took about 15 minutes. Within 24 hours, a provider reviewed my information and approved me for tirzepatide.

I didn't have a live video consultation—it was all done through forms and asynchronous review. For some people that's fine, but I prefer the personal interaction other services provide.

I was charged $499 upfront for the first 3 months.

First Shipment

My medication arrived 7 days after approval. The package included:

Three vials of compounded tirzepatide (enough for 3 months of treatment). Syringes and needles. Alcohol wipes. Basic instructions.

Everything was adequately packaged, though not as professionally presented as some larger competitors. The medication includes B6 (pyridoxine) as an additive, which they claim helps with side effects.

The Medication: Does It Work?

Yes, the compounded tirzepatide works as expected. I started at 2.5mg weekly and increased to 5mg, then 7.5mg over the 3 months.

Effects I noticed:

Strong appetite suppression. Reduced food cravings, especially sweets. Feeling full much faster. Better control over portion sizes.

Results over 3 months:

Weight lost: 26 pounds
Side effects: Mild nausea with dose increases, occasional digestive issues
B6 benefit: Hard to say if it actually helped with side effects
Overall effectiveness: Comparable to other compounded tirzepatide I've tried

The medication itself gets no complaints from me. It works.

The Coaching Component

Brello includes "personalized coaching" as part of their service. In practice, this means:

Periodic check-in messages through their portal. Educational content about weight loss. Basic accountability and support.

It's helpful but not particularly personalized. The coaching felt more like automated messaging with occasional human responses than truly customized support.

Customer Service Experience

This is where Brello loses points. I contacted customer service three times:

Shipping question: Took 2 days to get a response
Billing inquiry: Waited 36 hours for reply
Dose adjustment question: Response came next day, but felt rushed

They're not unresponsive, but definitely slower than competitors. And when you have questions about medication, waiting days for answers is frustrating.

The 3-Month Commitment: Pro or Con?

This is Brello's biggest differentiator—and biggest drawback, depending on your perspective.

The upside:

Lower monthly cost ($166 vs paying $250-300/month elsewhere). Ensures you stick with treatment long enough to see results. Don't have to worry about monthly payments.

The downside:

$499 upfront is a barrier for many people. No flexibility if you want to pause or change medications. Stuck for 3 months even if you have issues. Makes it harder to try before fully committing.

For me, the commitment wasn't ideal. I like the flexibility to adjust or stop if needed. Being locked in for 3 months felt restrictive.

Who Should Choose Brello Health?

Brello Health is good for:

People who can afford $499 upfront. Those who want to commit to at least 3 months of treatment. Anyone looking for mid-tier pricing with basic coaching. People comfortable with less hands-on customer service.

Not ideal for:

People who want month-to-month flexibility. Those who need responsive customer service. Anyone wanting to "try it for one month." People who prefer live consultations over forms. Users who value premium support and polish.

My Verdict

Brello Health offers competitive pricing and medication that works, but the 3-month commitment and slower customer service hold it back from being a top recommendation.

The medication quality is solid, and if you're confident you want to commit to tirzepatide for at least 3 months, the pricing makes sense. But the lack of flexibility and slower support are real drawbacks.

Rating: 4.3/5 stars

It's a decent service that works, but there are better options if you value flexibility and responsive support.

Bottom Line

Brello Health is fine. The medication works, pricing is competitive, and they deliver on their basic promises. But the mandatory 3-month commitment and slower customer service make it hard to enthusiastically recommend over more flexible, responsive competitors.

If you're certain about committing to tirzepatide for 3+ months and don't mind slower support, Brello can save you money. Otherwise, consider services with more flexibility.